Sabine Fièvre

This study shows that post-mitotic cortical neurons retain birthdate-dependent differentiation potential, with early-born neurons maintaining a broader repertoire than late-born neurons.

This study compares prenatal cortical development in two rodents, showing that major developmental milestones occur prenatally in Acomys, challenging the view that postnatal experience is essential for early brain maturation.

The paper investigates how environmental factors influence neocortical neuron fate and diversity through in vivo and in vitro experiments, showing population-specific responses and the importance of extracellular context.

This study shows that heterotopic neurons in EmlJ knockout mice retain functional properties similar to neocortical neurons despite their abnormal location.

The paper identifies regional differences in progenitor dynamics during brain development, showing sustained neurogenesis in the forebrain and transient neurogenesis in the hindbrain, driven by differences in cell cycle length and progenitor consumption.

This study identifies that the transcriptional identities of intracortically-projecting neurons primarily reflect their input-output connectivities rather than their birth dates or laminar positions.

This study shows that apical progenitors remain multipotent throughout cortical neurogenesis, reverting their temporal identity and generating neurons from earlier developmental stages.

The paper traces transcriptional trajectories of progenitors and neurons during mouse neocortex development, showing how molecular states from progenitors shape neuronal diversity.