Author

Daniela Sofía Abreu

University of MinhoORCID 0000-0002-6579-3596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

João Filipe OliveiraiD· 3 shared João Filipe VianaiD· 3 shared Alexandra VeigaiD· 2 shared João Luís MachadoiD· 2 shared Sara BarsantiiD· 2 shared Ali Mohammad Ibrahim-Alasoufi· 1 shared Ana João RodriguesiD· 1 shared Andreia Teixeira‐CastroiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersNeuroscience

João Filipe OliveiraORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hippocampal astrocytes contribute to encoding context-specific aversive stimuli to regulate fear-related behavior

Daniela Sofía Abreu, Alexandra Veiga, R. Jungmann, João Filipe Viana, Ana João Rodrigues, Carina Soares‐Cunha, João Filipe Oliveira

This study shows that hippocampal astrocytes encode context-specific aversive stimuli to regulate fear-related behavior through Ca2+ activity preceding freezing responses.

bioRxiv · May 24, 2026 · PreprintNeuroscience

Astrocytic AMPK couples metabolic signals to hypothalamic circadian timing

María Luengo-Mateos, Antía González-Vila, María Silveira-Loureiro, Daniela Sofía Abreu, Mikel Azkargorta, Ali Mohammad Ibrahim-Alasoufi, Víctor Pardo-García, Hugo Lopez-Goldar, Paula Martínez-Pérez, Helena Covelo-Molares, Nathalia Romanelli Vicente Dragano, Paola Fernández-Sanmartín, Ánxela Estévez‐Salguero, Mariana Astiz, Cláudia Cavadas, , Olga Barca‐Mayo

This study shows astrocytic AMPK links metabolic signals to hypothalamic circadian timing by regulating phosphoproteome organization and behavior.

bioRxiv · Aug 14, 2025 · PreprintNeuroscience

Astrocytic mGluR5 signaling tunes emotional and cognitive processing in the adult brain

João Filipe Viana, José Duarte Dias, Candela González-Arias, Luís Samuel Alves, Alexandra Veiga, Daniela Sofía Abreu, João Luís Machado, Sara Barsanti, Rui Jorge Nobre, Luís Pereira de Almeida, Gertrudis Perea, João Filipe Oliveira

This study investigates the role of astrocytic mGluR5 signaling in adult mice, showing its impact on emotional and cognitive behaviors through hippocampal function.

bioRxiv · Jul 7, 2025 · PreprintNeuroscience

Astrocytic Foxo1 regulates hippocampal spinogenesis and synaptic plasticity to enhance fear memory

João Filipe Viana, Sónia Guerra‐Gomes, Daniela Sofía Abreu, João Luís Machado, Sara Barsanti, Mariana Gonçalves, C. Martín, Vanessa Morais Sardinha, Diana Sofia Marques Nascimento, Gabriela Tavares, Martin Irmler, Johannes Beckers, Michał Korostyński, Nuno Sousa, Marta Navarrete, , João Filipe Oliveira

This study identifies Foxo1 as a key regulator of astrocytic calcium signaling in the hippocampus, influencing spinogenesis, synaptic plasticity, and fear memory.

bioRxiv · May 1, 2023 · PreprintNeuroscience