Martin Irmler

This study identifies sex-specific molecular differences in human skeletal muscle and shows that endurance training reduces these differences.

The paper identifies weaning body weight as a key predictor of adult diabetes in TALLYHO/JngJ mice, highlighting its relevance to childhood obesity research.

This study identifies Foxo1 as a key regulator of astrocytic calcium signaling in the hippocampus, influencing spinogenesis, synaptic plasticity, and fear memory.

CoNI integrates multi-omics data to identify genetic regulators of hepatic metabolism, validating several candidates in human liver cells and biopsies.

This study identifies HAND2 as an obesity-linked adipogenic transcription factor regulated by glucocorticoids, showing its role in adipocyte differentiation and its correlation with BMI in humans.

The paper predicts nanomaterial-induced chronic inflammation using in vitro measurements and in silico modeling by identifying mechanisms of nanomaterial cycling and quarantining in lung cells.

The paper identifies Wnt/PCP-activated Lgr5+ intestinal stem cells that directly differentiate into enteroendocrine or Paneth cells, challenging previous models of multipotency.