Author

Meng Amy Li

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0000-0002-6619-9919Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Austin G SmithiD· 3 shared Anish DattaniiD· 1 shared Ayaka YanagidaiD· 1 shared Buse Nurten Özel· 1 shared Daniel Spindlow· 1 shared Elena CarbogniniD· 1 shared Ge GuoiD· 1 shared Giuliano Giuseppe StirparoiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersDevelopmental Biology

Austin G SmithORCID

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3 papers

Recent·Most cited

Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 13, 2021

Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory

Masaki Kinoshita, Meng Amy Li, Michael Barber…·Austin G Smith

The paper shows that disabling de novo DNA methylation in embryonic stem cells causes them to adopt a trophoblast fate instead of proper differentiation, due to misexpression of Ascl2.

20 citations

mouseDNA methylation

𝕏 PostBluesky

Developmental BiologyCell stem cellPeer-reviewedApr 7, 2021

Human Naive Epiblast Cells Possess Unrestricted Lineage Potential

Ge Guo, Giuliano Giuseppe Stirparo, Stanley E. Strawbridge…·Austin G Smith

The paper shows human naive epiblast cells can generate trophectoderm and trophoblast cells, unlike mouse embryonic stem cells, and identifies key regulators of this process.

355 citationstop 1%

humanbulk RNA-seq

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Developmental BiologyThe EMBO JournalPeer-reviewedNov 27, 2018

A common molecular logic determines embryonic stem cell self-renewal and reprogramming

Sara-Jane Dunn, Meng Amy Li, Elena Carbognin…·Graziano Martello

This study identifies a common molecular logic governing embryonic stem cell self-renewal and reprogramming through Boolean network analysis and experimental validation.

51 citations

mousebulk RNA-seq

𝕏 PostBluesky