Author

Valerie C. Bracchi-Ricard

Drexel UniversityORCID 0000-0002-6658-4374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

John R. BetheaiD· 3 shared Tetyana MartynyukiD· 2 shared Veronica J. TomiD· 2 shared Aravind MeyyappaniD· 1 shared Brian T. GaudetteiD· 1 shared Daniela RicciiD· 1 shared David AllmaniD· 1 shared Erin C. JonesiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

John R. BetheaORCID

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Author profile →

3 papers

Recent·Most cited

Hippocampal CA3 Nex/Neurod6+ neuron-specific TNFR2 alleviates chronic neuropathic pain by sex-dependently engaging opioid and endocannabinoid pathways

Sreejita Arnab, Payam A. Fathi, Erin C. Jones, Aravind Meyyappan, Kayla L. Nguyen, Valerie C. Bracchi-Ricard, Shruti Gupta, Roman Fischer, Veronica J. Tom, John R. Bethea

This study shows that TNFR2 signaling in hippocampal Nex/Neurod6 neurons is critical for chronic neuropathic pain recovery, acting through sex-dependent opioid and endocannabinoid pathways.

bioRxiv · Nov 24, 2025 · PreprintPharmacology & Toxicology

Mitigating sTNF/TNFR1 activation on VGluT2+ spinal cord interneurons improves immune function after mid-thoracic spinal cord injury

Tetyana Martynyuk, Jerome Ricard, Valerie C. Bracchi-Ricard, Samuel Price, Jenna R. McGrath, Kimberly J. Dougherty, Veronica J. Tom, John R. Bethea

bioRxiv · Jul 9, 2024Neuroscience

Increased activity of IRE1 improves the clinical presentation of EAE

Valerie C. Bracchi-Ricard, Kayla Nguyen, Daniela Ricci, Brian T. Gaudette, Jorge Henao‐Mejia, Roberta Brambilla, Tetyana Martynyuk, Tali Gidalevitz, David Allman, John R. Bethea, Yair Argon

This study shows that increased IRE1 activity in a mouse model of EAE reduces inflammation and improves motor function, suggesting context-dependent protective effects of ER stress.

The FASEB Journal · Nov 20, 2023Peer-reviewedNeuroscience