Author

Daniela Ricci

Children's Hospital of PhiladelphiaORCID 0000-0003-3787-920XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alice NevoneiD· 1 shared Brian T. GaudetteiD· 1 shared Caroline DemangeliD· 1 shared Chloé Veront· 1 shared David AllmaniD· 1 shared David HardyiD· 1 shared Florence Bugault· 1 shared Irene VALCOZZENA· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Alice NevoneORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting Sec61 to Silence Pathogenic Light-Chain Production in AL Amyloidosis

Daniela Ricci, Chloé Veront, Irene VALCOZZENA, Merlin Després, Alice Nevone, Marine Oberkampf, Mariette Matondo, Karen Druart, Thibaut Douché, Sarra Loulizi, David Hardy, Florence Bugault, Manon Capdeville, Mario Nuvolone, Caroline Demangel

This study targets the Sec61 translocon to suppress pathogenic light-chain production in AL amyloidosis, showing that mycolactone and synthetic inhibitors like A317 reduce LC secretion while highlighting the need for client selectivity.

bioRxiv · Sep 13, 2026 · PreprintCell Biology

Increased activity of IRE1 improves the clinical presentation of EAE

Valerie C. Bracchi-Ricard, Kayla Nguyen, Daniela Ricci, Brian T. Gaudette, Jorge Henao‐Mejia, Roberta Brambilla, Tetyana Martynyuk, Tali Gidalevitz, David Allman, John R. Bethea, Yair Argon

This study shows that increased IRE1 activity in a mouse model of EAE reduces inflammation and improves motor function, suggesting context-dependent protective effects of ER stress.

The FASEB Journal · Nov 20, 2023Peer-reviewedNeuroscience