Author

Brian T. Gaudette

Cleveland ClinicORCID 0000-0001-6627-3085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

David AllmaniD· 2 shared Daniela RicciiD· 1 shared David B. WeineriD· 1 shared Isaiah RozichiD· 1 shared Ivan P. MaillardiD· 1 shared Jeffrey R. MaslankaiD· 1 shared Jennifer LondreganiD· 1 shared John R. BetheaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

David AllmanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedJul 30, 2026

Notch2 signaling instructs viral and bacterial TLR responsiveness in B cells

Jennifer Londregan, Isaiah Rozich, Brian T. Gaudette…·David Allman

This study shows Notch2 signaling enhances TLR3 and TLR4 responsiveness in MZ B cells, promoting immune responses to viral and bacterial pathogens.

DOI 10.1016/j.celrep.2026.117748

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceThe FASEB JournalPeer-reviewedNov 20, 2023

Increased activity of IRE1 improves the clinical presentation of EAE

Valerie C. Bracchi-Ricard, Kayla Nguyen, Daniela Ricci…·Yair Argon

This study shows that increased IRE1 activity in a mouse model of EAE reduces inflammation and improves motor function, suggesting context-dependent protective effects of ER stress.

4 citations

mouseexperimental assay

𝕏 PostBluesky