Author

Tsuyoshi Takata

Tohoku UniversityORCID 0000-0002-6691-2569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Hozumi MotohashiiD· 2 shared Masanobu MoritaiD· 2 shared Takaaki AkaikeiD· 2 shared Tetsuro MatsunagaiD· 2 shared Tomoaki IdaiD· 2 shared Akira NishimuraiD· 1 shared Ayumi MitsuneiD· 1 shared Ayumi SuzukiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

Hozumi MotohashiORCID

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2 papers

Recent·Most cited

Sulfide:quinone oxidoreductase drives mitochondrial supersulfide metabolism to regulate bioenergetics and longevity in eukaryotes

Jia Yao, Tetsuro Matsunaga, Akira Nishimura, Meg Shieh, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Tsuyoshi Takata, Uladzimir Barayeu, Hozumi Motohashi, Masanobu Morita, Takaaki Akaike

This study shows that SQR is essential for mitochondrial function and longevity by regulating sulfur respiration and supersulfide metabolism in yeast and mice.

bioRxiv · Apr 7, 2026 · PreprintBiochemistry

Glutathione supersulphide regulates T-cell receptor signalling

Yusaku Sasaki, Tadahisa Numakura, Mitsuhiro Yamada, Hisatoshi Sugiura, Tetsuro Matsunaga, Tomoaki Ida, Masanobu Morita, Ayumi Suzuki, Shuichiro Matsumoto, Madoka Kawaguchi, Takeshi Kawabe, Shunichi Tayama, Yuko Okuyama, Tsuyoshi Takata, Kenji Inaba, , Hozumi Motohashi

This study shows that glutathione supersulphide regulates T-cell receptor signalling by interacting with the CD3ε chain, affecting TCR activation and inflammation.

bioRxiv · Apr 30, 2024 · PreprintBiochemistry