Gut microbial metabolite imidazole propionate impairs endothelial cell function and promotes the development of atherosclerosis
Vanasa Nageswaran, Alba Carreras, Leander Reinshagen, Katharina R. Beck, Jakob Steinfeldt, Marcus Henricsson, Pegah Ramezani Rad, Lisa Peters, Elisabeth Tamara Strässler, J.J. Lim, Barbara J. H. Verhaar, Yvonne Döring, Christian Weber, Maximilian König, Elisabeth Steinhagen‐Thiessen, , Arash Haghikia
This study shows that gut microbial metabolite imidazole propionate impairs endothelial function and promotes atherosclerosis in both human and animal models.
Arteriosclerosis Thrombosis and Vascular Biology · Mar 27, 2025Peer-reviewedSystems Biology