Søren Grubb

The paper characterizes primary cilia and centriole organization in mouse and human brain microvasculature, revealing interspecies differences and their potential role in sensing microenvironmental signals.

This study examines how brain precapillary sphincters regulate capillary blood flow in adult and aged mice during blood pressure surges, showing diminished myogenic response in older mice.

This study identifies distinct Ca2+ signaling profiles in leptomeningeal fibroblast subgroups in awake mice under health and inflammation conditions.

The paper investigates microglial interactions with cerebral vasculature using electron microscopy data, finding that 20% of microglia form direct contacts through gaps between astrocyte endfeet.

The paper examines the ultrastructural pathways of brain waste clearance, highlighting the role of macrophages and arachnoid villi in transporting waste to the venous system.

This study uses 3D electron microscopy to examine the neurovascular unit, revealing new structural roles for precapillary sphincters, collagen, and astrocytic endfeet in neurovascular coupling.

This study identifies age-related impairments in brain microvascular dynamics, particularly in precapillary sphincters, leading to reduced neurovascular function in aging.

This study identifies precapillary sphincters as regulators of cerebral blood flow, showing their dilation and constriction in response to neural activity and ischemia.