Author

James Hunter MacCabe

King's College LondonORCID 0000-0002-6754-1018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Adrian HaydayiD· 1 shared Aiden Peter CorviniD· 1 shared Alexander L. RichardsiD· 1 shared Amy L. GillespieiD· 1 shared Andew McQuillin· 1 shared Annabel BorgiD· 1 shared Antonia LandwehriD· 1 shared Bart P. F. RutteniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Adrian HaydayORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The antipsychotic drug clozapine suppresses autoimmunity driving psychosis-like behavior in mice

Le D. He, Harriet Feldman, Timothy Nguyen, Marion Bosc, Vasishta Polisetty, Orla Kriel, Antonia Landwehr, Annabel Borg, Fernanda Teixeira Subtil, Mohammadparsa Khakpour, Jitong Zhou, Svend Kjær, James Hunter MacCabe, Thomas Arthur Pollak, Marie‐Ève Tremblay, , Katharina Schmack

This study shows clozapine reduces anti-NMDAR autoantibodies and psychosis-like behaviors in mice by suppressing autoimmunity.

bioRxiv · Mar 31, 2026 · PreprintNeuroscience

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

Eilis J. Hannon, Emma Louise Dempster, Georgina Mansell, Joe Burrage, Nicholas James Bass, Marc M. Bohlken, Aiden Peter Corvin, Charles J. C. Curtis, David W. Dempster, Marta Di Forta, Timothy G. Dinan, Gary J Donohoe, Fiona Gaughran, Michael Gill, Amy L. Gillespie, , Jonathan S. Mill

This study identifies DNA methylation changes in blood samples from psychosis patients, including treatment-resistant schizophrenia, and links them to biological age, smoking, and cellular composition.

bioRxiv · Apr 5, 2020 · PreprintGenomics