Author

Tod A. Leighfield

National Oceanic and Atmospheric AdministrationORCID 0000-0002-6780-8800Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel L. MinoriD· 1 shared Davide ProvasiiD· 1 shared Eduard NeuiD· 1 shared Elizabeth R. ParkiD· 1 shared Holly S. HajareiD· 1 shared J. Du BoisiD· 1 shared John V. MulcahyiD· 1 shared Kandis M. ArlinghausiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Daniel L. MinorORCID

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1 paper

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedApr 24, 2025

Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins

Sandra Zakrzewska, Samantha A. Nixon, Zhou Chen…·Daniel L. Minor

This paper identifies the structural basis for saxitoxin congener binding and neutralization by saxiphilins, showing how these proteins sequester toxins and reverse sodium channel blockage.

6 citations

proteomicsexperimental assay

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