Author

Taekyung D. Yun

Columbia University Irving Medical CenterORCID 0000-0002-6790-3672Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Delfina LarreaiD· 2 shared Estela Área-GómeziD· 2 shared Rishi R. AgrawaliD· 2 shared Alexander S. GalkiniD· 1 shared Belem Yoval‐SáncheziD· 1 shared Donghui SongiD· 1 shared Emily R. LowryiD· 1 shared Frank MacalusoiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Delfina LarreaORCID

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2 papers

Recent·Most cited

Alzheimer's-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury

Rishi R. Agrawal, Delfina Larrea, Yimeng Xu, Lingyan Shi, Hylde Zirpoli, Leslie Gunther-Cummins, Valentina Emmanuele, Donghui Song, Taekyung D. Yun, Frank Macaluso, Wei Min, Steven G. Kernie, Richard Joseph Deckelbaum, Estela Área-Gómez

The paper investigates how traumatic brain injury (TBI) increases mitochondria-associated ER membranes (MAMs) and C99 levels, linking these changes to Alzheimer's disease (AD) through lipid metabolism alterations.

Cellular and Molecular Neurobiology · Dec 26, 2022Peer-reviewedNeuroscience

Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

Delfina Larrea, Kirstin A. Tamucci, Khushbu Kabra, KEVIN R. VELASCO, Taekyung D. Yun, Marta Pera, Jorge Montesinos, Rishi R. Agrawal, John W. Smerdon, Emily R. Lowry, Анна Степанова, Belem Yoval‐Sánchez, Alexander S. Galkin, Hynek Wichterle, Estela Área-Gómez

This study shows that disrupted MAM function in ALS models leads to altered mitochondrial metabolism, specifically a shift from pyruvate to fatty acid utilization.

bioRxiv · Sep 22, 2022 · PreprintMolecular Biology