Author

Kar Muthumani

The Wistar InstituteORCID 0000-0002-6807-2065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Assay:imaging· 1

Frequent Co-Authors

Joel A. CasseliD· 2 shared Amanda Pires BonfantiiD· 1 shared Amit Bar‐OriD· 1 shared Emmanouil PapasavvasiD· 1 shared Gauri MirjiiD· 1 shared Hiroaki TatenoiD· 1 shared Hsin‐Yao TangiD· 1 shared Isabela Batista OlivaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Joel A. CasselORCID

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2 papers

Recent·Most cited

ImmunologyCancer ResearchPeer-reviewedNov 3, 2025

Targeting Siglec-10/α3β1 Integrin Interactions Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer

Pratima Saini, Gauri Mirji, S M Shamsul Islam…·Mohamed Abdel‐Mohsen

This paper identifies Siglec-10/α3β1 integrin interactions as a mechanism suppressing macrophage phagocytosis in PDAC and shows that targeting these interactions enhances anti-tumor immunity.

15 citationstop 3%

humanmouse

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ImmunologyThe Journal of ImmunologyPeer-reviewedAug 7, 2024

Cloning and functional characterization of novel human neutralizing anti-interferon-alpha and anti-interferon-beta antibodies

Emmanouil Papasavvas, Lily D. Lu, Matthew G. Fair…·Luis J. Montaner

The paper isolates and characterizes neutralizing anti-interferon-alpha and anti-interferon-beta antibodies from human patients, showing their specificity and potential therapeutic applications.

DOI 10.4049/jimmunol.2400265

humanproteomics

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