Human Elp3/Kat9 is a mitochondrial tRNA modifying enzyme
Rachid Boutoual, Hyunsun Jo, Indra Heckenbach, Ritesh Tiwari, Herbert G. Kasler, Chad A. Lerner, Samah Shah, Birgit Schilling, Vincenzo Calvanese, Matthew J. Rardin, Morten Scheibye‐Knudsen, Eric M. Verdin
The paper identifies mt-ELP3 as a mitochondrial tRNA modifying enzyme that protects mt-tRNAs from degradation and enhances mitochondrial translation and OXPHOS complex expression.
bioRxiv · Mar 24, 2022 · PreprintMolecular Biology