Molecular BiologyThe EMBO JournalPeer-reviewed
Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity
Aniruddha Das, Pankaj Singh Thapa, Ulises Santiago…·Wojciech Pokrzywa
The paper investigates how the CHN-1/UFD-2 complex enhances ubiquitin chain formation through dimerization and chaperone-mediated regulation of substrate ubiquitylation.
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