Author

Noah S. Butler

University of IowaORCID 0000-0002-1429-0796Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alejandro A. PezzuloiD· 1 shared Alexander D. ClausseniD· 1 shared Alicia M. QuesneliD· 1 shared Andrea MarziiD· 1 shared Andrew L. ThurmaniD· 1 shared Brian J. MostaertiD· 1 shared Bryce HungeriD· 1 shared Caitlin O. Messingham· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alejandro A. PezzuloORCID

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2 papers

Recent·Most cited

Establishment of a cochlear lymphatic vascular network and immune surveillance system following cochlear implantation

Muhammad Taifur Rahman, Ibrahim Razu, Shakila Mahmuda Fatima, Brian J. Mostaert, Bryce Hunger, Md. F. Hossain, Diana Correa, Jennifer T. O’Malley, Nashwaan Ali Khan, Zhenshen Zhang, Osama Tarabichi, Ya Lang Enke, Robert D. Gay, Jacob Oleson, Noah S. Butler, , Marlan Rex Hansen

This study identifies a lymphatic vascular network and immune surveillance system in the cochlea following implantation, contributing to inflammatory responses.

bioRxiv · Oct 26, 2026 · PreprintSystems Biology

Acute malaria dysregulates specialized lymph node macrophages to suppress vaccine-elicited protection against Ebola virus

Jonah M. Elliff, Lindsey Grady, Kyle Lee O’Donnell, Caitlin O. Messingham, Kai J. Rogers, Jobaida Akther, Andrew L. Thurman, Rahul Vijay, Alejandro A. Pezzulo, Troy D. Randall, Andrea Marzi, Noah S. Butler, Wendy J. Maury

This study shows that acute malaria infection reduces the effectiveness of a low-dose Ebola vaccine by impairing antibody responses in lymph node macrophages, which can be mitigated with higher vaccine doses.

mBio · Dec 30, 2025Peer-reviewedMicrobiology