Author

Joe G. N. Garcia

Mayo ClinicORCID 0000-0002-6934-0420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adaani FrostiD· 1 shared Alexander Y. Tchourbanov· 1 shared Amit AroraiD· 1 shared Andre FrankeiD· 1 shared Andrea OlschewskiiD· 1 shared Andrew J. PeacockiD· 1 shared Anna UlrichiD· 1 shared Anton Vonk NoordegraafiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adaani FrostORCID

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2 papers

Recent·Most cited

Small Molecule Degradation of the microRNA-21 Precursor Rescues Pathogenic Pathways in Cellular Models of Fibrosis

Tenghui Wang, Xueyi Yang, Yeongju Lee, Jin Hyang Song, Jessica L. Childs‐Disney, Joe G. N. Garcia, Matthew David Disney

This study shows that degrading the miR-21 precursor with TGP-21-RiboTAC reduces pathogenic pathways in fibrosis models by reactivating tumor suppressor genes.

ACS Chemical Biology · May 18, 2026Peer-reviewedBiochemistry

Genetic determinants of risk and survival in pulmonary arterial hypertension

Christopher J. Rhodes, Ken Batai, Marta Bleda, Matthias Haimel, Laura Southgate, Marine Germain, Michael W. Pauciulo, Charaka Hadinnapola, Jurjan Aman, Barbara Girerd, Amit Arora, Jo Knight, Ken Benjamin Hanscombe, Jason H. Karnes, Marika Kaakinen, , Quinten Waisfisz

This study identifies common genetic variants associated with pulmonary arterial hypertension risk and survival, focusing on HLA-DPA1/DPB1 and a SOX17 enhancer locus.

The Lancet Respiratory Medicine · Dec 5, 2018Peer-reviewedGenetics