Author

Petras P. Dzeja

Mayo ClinicORCID 0000-0002-7014-9930Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

Song ZhangiD· 2 shared Adam L Jaspersen· 1 shared Alexander S. GalkiniD· 1 shared Amirrasoul TavakoliiD· 1 shared Andrea StojakoviciD· 1 shared Angeles Fernandez-Gonzalez· 1 shared Anthony Sheu· 1 shared Benjamin Gateno· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Song ZhangORCID

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2 papers

Recent·Most cited

The cryo-EM structure of mouse radial spoke 3 reveals a unique metabolic and regulatory hub in cilia

Yanhe Zhao, Kangkang Song, Amirrasoul Tavakoli, Long Gui, Angeles Fernandez-Gonzalez, Song Zhang, Petras P. Dzeja, S. Alex Mitsialis, Xuewu Zhang, Daniela Nicastro

The paper determines the 3D structure of mouse radial spoke 3 (RS3) using cryo-EM and identifies its role as a metabolic and regulatory hub in ciliary motility.

Nature Structural & Molecular Biology · Jun 27, 2025Peer-reviewedBiophysics

Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimers mouse model

Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace A. Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal K. Dehankar, Cory C. Funk, Jordan Maximillian Wilkins, Анна Степанова, , Eugenia V. Trushina

The paper shows that partial inhibition of mitochondrial complex I protects against neurodegeneration in Alzheimer's mice by improving energy homeostasis, synaptic function, and reducing inflammation.

Communications Biology · Jan 8, 2021Peer-reviewedNeuroscience