Author
The University of Texas Southwestern Medical CenterORCID 0000-0002-3634-6711Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jie Li, Jay Xiaojun Tan, Zhijian J. Chen…·Xiao-Chen Bai
This study identifies phosphoinositides and cholesterol as regulators of STING activation by promoting its oligomerization and translocation.
Jay Xiaojun Tan, Bo Lv, Jie Li…·Zhijian J. Chen
This study identifies PtdIns(3,5)P2 as an endogenous ligand of STING that cooperates with cGAMP to activate innate immune signaling.
Hui Zhang, Xiao‐chen Bai, Xuewu Zhang
The paper determines the cryo-EM structure of the IL-17RA, IL-17RB, and ACT1 complex, revealing how these proteins form a hetero-tetramer to initiate immune signaling.
Yanhe Zhao, Kangkang Song, Amirrasoul Tavakoli…·Daniela Nicastro
The paper determines the 3D structure of mouse radial spoke 3 (RS3) using cryo-EM and identifies its role as a metabolic and regulatory hub in ciliary motility.
Zeguo Sun, Zhengzi Yi, Chengguo Wei…·Weijia Zhang
The paper identifies four SNPs in the LILRB3 gene associated with graft failure in African American kidney transplant recipients and links them to immune-related diseases.