This study profiles allele-specific expression across 42 tissues and 34 pig breeds using an open-source pipeline, revealing widespread and tissue-specific allelic imbalance.

Genome biology · Jun 29, 2026Peer-reviewedGenomics

Genomic Insights into the Demographic History and Local Adaptation of Wild Boars Across Eurasia

Zishuai Wang, Zixin Li, Tao Huang, Jianhai Chen, Pan Xu, Ruimin Qiao, Hongwei Holly Yin, Chengyi Song, Dongjie Zhang, Di Liu, Shuhong Zhao, Martien A. M. Groenen, Ole Madsen, Yanlin Zhang, Lijing Bai, Kui Li

The paper analyzes whole-genome data from wild boars to trace their demographic history and identify genetic signatures of local adaptation in Central Asia.

Cell Genomics · Jul 24, 2025Peer-reviewedEvolutionary Biology

Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of complex traits in pig.

Zhiting Xu, Qing Lin, Xiaodian Cai, Zhanming Zhong, Jinyan Teng, Bingjie Li, Haonan Zeng, Yahui Gao, Zexi Cai, Xiaoqing Wang, Liangyu Shi, Xue Wang, Yi Wang, Zipeng Zhang, Yu Lin, , Zhe Zhang

The paper performs a multi-breed meta-GWAS in pigs to identify genomic regions associated with complex traits and integrates with PigGTEx to prioritize variant-gene-tissue-trait circuits.

National Science Review · Feb 14, 2025Peer-reviewedGenetics

A compendium of genetic regulatory effects across pig tissues

Jinyan Teng, Yahui Gao, Hongwei Holly Yin, Zhonghao Bai, Shuli Liu, Haonan Zeng, Lijing Bai, Zexi Cai, Bingru Zhao, Xiujin Li, Zhiting Xu, Qing Lin, Zhangyuan Pan, Wenjing Yang, Xiaoshan Yu, , George E. Liu

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

Nature Genetics · Jan 1, 2024Peer-reviewedGenomics