Genomic and phenomic insights from an atlas of genetic effects on DNA methylation
Josine L. Min, Gibran Hemani, Eilis J. Hannon, Koen F. Dekkers, Juan Castillo Fernandez, René Luijk, Elena Carnero‐Montoro, Daniel John Lawson, Kimberley Burrows, Matthew J Suderman, Andrew D. Bretherick, Tom G. Richardson, Johanna Klughammer, Valentina Iotchkova, Gemma C. Sharp, , Marinus H. van IJzendoorn
The paper identifies genetic variants influencing DNA methylation in blood and shows their associations with complex traits and diseases, but finds limited direct causality.
Nature Genetics · Sep 1, 2021Peer-reviewedGenetic & Genomic Medicine