uniSynK: a ratio-optimized bicistronic chemically induced dimerization tool for robust induction of dendritic spine enlargement
Kota Homma, Masanari Ohtsuka, Siqi Zhou…·Takeshi Sawada
The paper develops uniSynK, a single-vector chemogenetic tool that optimizes the expression ratio of two components to robustly induce dendritic spine enlargement with fewer off-target effects.