Author

Kent Imaizumi

Stanford MedicineORCID 0000-0002-3565-5248Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Sergiu P. PașcaiD· 3 shared Kevin W. KelleyiD· 2 shared Mayuri Vijay TheteiD· 2 shared Rebecca J. LevyiD· 2 shared Abel BermudeziD· 1 shared Amander ClarkiD· 1 shared Anne BrunetiD· 1 shared Arpana Arjun McKinney· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Sergiu P. PașcaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human organoid screen links transient translational modulation to progenitor progression in corticogenesis

Merve Avar, Travis C Lantz, Daniel Heinzer, Massimo M Onesto, Kent Imaizumi, Vrishika Kulur, Marcos AS Fonseca, Sejin Yoon, Chunyang Dong, Becky J Levy, Min-Yin Li, Enrique Sosa, Abel Bermudez, Delaney Wood, Isabelle Liu, , Sergiu P Pasca

The paper screens human cortical organoids with small molecules to identify translational modulators affecting progenitor progression in corticogenesis, finding Emetine promotes neuronal differentiation.

bioRxiv · Nov 6, 2026 · PreprintNeuroscience

Human assembloid model of the ascending neural sensory pathway

Ji‐il Kim, Kent Imaizumi, Ovidiu F. Jurjuţ, Kevin W. Kelley, Dong Wang, Mayuri Vijay Thete, Zuzana Hudáčová, Neal D. Amin, Rebecca J. Levy, Grégory Scherrer, Sergiu P. Pașca

This study creates a human assembloid model of the ascending somatosensory pathway using pluripotent stem cells and demonstrates its functional connectivity and response to pain-related stimuli.

Nature · Apr 9, 2025Peer-reviewedNeuroscience

CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development

Xiangling Meng, David Yao, Kent Imaizumi, Xiaoyu Chen, Kevin W. Kelley, Noah Reis, Mayuri Vijay Thete, Arpana Arjun McKinney, Shravanti Kulkarni, Georgia Panagiotakos, Michael Cory Bassik, Sergiu P. Pașca

The paper uses CRISPR screens in human forebrain assembloids to identify NDD genes involved in interneuron generation and migration, revealing novel roles for the ER in migration.

Nature · Sep 27, 2023Peer-reviewedNeuroscience

Novel System to Monitor In Vivo Neural Graft Activity After Spinal Cord Injury

Kentaro Ago, Narihito Nagoshi, Kent Imaizumi, Takahiro Kitagawa, Momotaro Kawai, Keita Kajikawa, Reo Shibata, Yasuhiro Kamata, Kota Kojima, Munehisa Shinozaki, Takahiro Kondo, Satoshi Iwano, Atsushi Miyawaki, Masanari Ohtsuka, Haruhiko Bito, , Hideyuki Okano

This paper introduces a non-invasive in vivo imaging system to monitor neural graft activity after spinal cord injury and shows graft integration with host behavior.

bioRxiv · Aug 29, 2021 · PreprintNeuroscience