Longitudinal single-cell and spatial transcriptomics reveals intratumor heterogeneity, therapeutic response, and comparative value of canine marginal zone lymphoma
Grace E. Walker, Marissa G. Macchietto, Kelly Reid…·Amy E. Treeful
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University of MinnesotaORCID 0000-0002-7098-301XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Grace E. Walker, Marissa G. Macchietto, Kelly Reid…·Amy E. Treeful
Yogesh Budhathoki, Matthew V. Cannon, Troy A. McEachron…·Ryan David Roberts
This study integrates single-cell and spatial transcriptomic data across species to identify conserved and distinct tumor ecosystems in osteosarcoma, revealing canine models as more faithful and highlighting ECM signaling in metastatic lesions.
Daniel Fuchs, Armin Jarosch, Erin Beebe…·Enni Markkanen
This study compares multiomic profiles of human and canine soft-tissue sarcomas, revealing molecular similarities and identifying clinically relevant subgroups.
Kate Megquier, Jason Turner-Maier, Ross Swofford…·Kerstin Lindblad‐Toh
The paper compares genomic features of canine and human angiosarcoma, finding shared genes and pathways, suggesting dogs as a valuable model for studying this cancer.
Aaron L. Sarver, Anne E. Sarver, Ce Yuan, Subbaya Subramanian
OMCD provides a web-based database for pan-cancer miRNA expression analysis, enabling visualization, statistical analysis, and exploration of miRNA clusters across cancer types.