Author

Eyal Metzl-Raz

Stanford MedicineORCID 0000-0002-7111-2822Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aaron D. GitleriD· 1 shared Aaron Hidalgo· 1 shared Anshul Bharat KundajeiD· 1 shared Betty B. LiuiD· 1 shared Birgitt SchüleiD· 1 shared Caitlin Ann TayloriD· 1 shared Callista Stephanie YeeiD· 1 shared Casey A. GiffordiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aaron D. GitlerORCID

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3 papers

Recent·Most cited

Decoding Chromatin Dynamics in Cardiac Organoids Reveals Genetic Drivers of Human Heart Development and Disease

Eyal Metzl-Raz, Ryan Zhao, Salil Deshpande, Yassine Zouaghi, Jackson Ross Powell, Megha Agarwal, Betty B. Liu, Samuel H. Kim, Immanuel Abdi, Ivy Evergreen, Maya U. Sheth, Elizabeth G. Poulsen Porter, Joshua Rico, Matthew Miyamoto, Julie M. Sanchez, , Casey A. Gifford

The paper uses a single-cell multi-omic atlas and deep learning to identify cis-regulatory elements and genetic drivers of heart development and disease.

bioRxiv · Oct 15, 2025 · PreprintGenetics

Histone deacetylase inhibition expands cellular proteostasis repertoires to enhance neuronal stress resilience

Caitlin Ann Taylor, Maya Maor-Nof, Wendy A. Herbst, Shihong Max Gao, Xinyue Li, Eyal Metzl-Raz, Aaron Hidalgo, Faria Zafar, Callista Stephanie Yee, Birgitt Schüle, Meng Carla Wang, Aaron D. Gitler, Kang Shen

This study shows that inhibiting histone deacetylases enhances neuronal resilience to stress by inducing a permissive transcriptional state and activating proteostasis pathways.

bioRxiv · Aug 21, 2024 · PreprintNeuroscience

Gene transcription as a limiting factor in protein production and cell growth

Eyal Metzl-Raz, Moshe Kafri, Gilad Yaakov, Naama Barkai

The paper investigates how gene transcription limits protein production and cell growth by analyzing the effects of transcriptional feedback and its impact on cell size and division time.

G3 Genes Genomes Genetics · Jul 21, 2020Peer-reviewedSystems Biology