Matthew O. Parker

Neural and Behavioral Dynamics of Acute Fentanyl Administration and Implications for Hazard Assessment of Novel Synthetic Opioids in Larval Zebrafish

This study uses larval zebrafish to assess the behavioral and neural effects of fentanyl and other synthetic opioids, identifying potential mechanisms and validating a scalable model for hazard assessment.

Virtual reality exposes fine-scale alterations in behaviour following loss of the ADHD-linked gene adgrl3.1 in zebrafish

The paper uses virtual reality to assess behavioural changes in ADHD-linked adgrl3.1 mutant zebrafish, revealing heightened excitability and lower motor threshold.

Fentanyl and Alcohol Co-Exposure Induce Robust, Sustained Hyperlocomotion and Neural Circuit Disruption in Larval Zebrafish

This study investigates the combined effects of fentanyl and alcohol in larval zebrafish, finding robust hyperlocomotion and neural circuit disruption.

Genetic disruption of leucine rich repeat transmembrane protein 4 like 1 induces a pro-social behavioural phenotype in zebrafish

This study shows that knocking out lrrtm4l1 in zebrafish leads to more social behavior, including cohesive shoaling and reduced aggression.

Environmental Enrichment Reduces adgrl3.1-Related Anxiety and Attention Deficits but Not Impulsivity

This study shows environmental enrichment reduces anxiety and attention deficits but not impulsivity in adgrl3.1 knockout zebrafish, indicating genetic and environmental interactions in behavioral traits.

Social Isolation Intensifies adgrl3.1-Related Externalizing and Internalizing Behaviors in Zebrafish

The paper examines how social isolation interacts with a genetic mutation to intensify both externalizing and internalizing behaviors in zebrafish.

Spatiotemporal dynamics of locomotor decisions in Drosophila melanogaster

This study examines spatiotemporal dynamics of locomotor decisions in Drosophila and humans, showing that future choices can be predicted through sustained locomotor signatures and highlighting the role of sensory and dopaminergic signaling.

The effect of laboratory diet and feeding on growth parameters in zebrafish

This study identifies an insect-based diet as optimal for juvenile zebrafish growth and highlights the need for standardized feeding protocols to improve reproducibility and welfare.

adgrl3.1-deficient zebrafish show noradrenaline-mediated externalizing behaviors, and altered expression of externalizing disorder-candidate genes, suggesting functional targets for treatment

This study shows adgrl3.1-deficient zebrafish exhibit externalizing behaviors rescued by atomoxetine, and identifies differentially expressed genes linked to externalizing disorders.

Transgenerational Effects of Early-Life Stress on Anxiety in Zebrafish (Danio rerio)

This study shows that early-life stress in zebrafish affects anxiety-related behaviors and these effects are transgenerational across three generations.

Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

The paper identifies Slit3 as a genetic locus influencing nicotine preference in zebrafish and smoking behavior in humans through mutagenesis screens and SNP analysis.

A fully automated computer based Skinner box for testing learning and memory in zebrafish

This paper introduces a fully automated Skinner box for testing learning and memory in zebrafish, enabling standardized behavioral assays for cognitive function studies.