Author

Zhengkuan Tang

Harvard UniversityORCID 0009-0006-2922-4210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandru M. PleşaiD· 1 shared Andrew L. JiiD· 1 shared Anna MandinovaiD· 1 shared Asaf Ashkenazy-Titelman· 1 shared Boyu Jiang· 1 shared Brody A. DemingiD· 1 shared Chongli YuaniD· 1 shared D.D. Majewski· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Alexandru M. PleşaORCID

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2 papers

Recent·Most cited

NeuroscienceTranslational PsychiatryPeer-reviewedJul 31, 2026

Single-nucleus transcriptomics reveal disrupted pathways in the prefrontal cortex of Scn2a-deficient mice

Ye-Eun Yoo, Zaiyang Zhang, Purba Mandal…·Yang Yang

This study uses snRNA-seq to analyze gene expression changes in Scn2a-deficient mice, identifying disrupted pathways in neuronal subtypes of the prefrontal cortex.

DOI 10.1038/s41398-026-04348-0

mousesnRNA-seq

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Synthetic BiologyJournal of Investigative DermatologyPeer-reviewedJul 21, 2026

Human skin rejuvenation via mRNA

Li Li, Zhengkuan Tang, Xavier Portillo…·George McDonald Church

This paper presents a single-cell atlas of skin aging and identifies ATF3 as a regulator of aging, leading to an mRNA-based treatment that reduces cell senescence and enhances skin rejuvenation.

6 citationstop 3%

humanscRNA-seq

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