Tafazzin-Mediated Cardiolipin Remodeling Controls Metabolic Stress Response and Effector Function of Inflammatory T Cells
Xiufeng Zhao, Sophia M. Hochrein, Miriam Eckstein, Hao Wu, Katrin Sinning, Katharina J. Ermer, Sarah‐Lena Puhl, Martin Eilers, Werner Schmitz, Christian Stigloher, Steven Michael Claypool, Christoph Maack, Jan Dudek, Martin Vaeth
This study shows that Tafazzin-mediated cardiolipin remodeling is essential for metabolic stress response and effector function of inflammatory T cells, with implications for Barth syndrome.
bioRxiv · Aug 25, 2025 · PreprintImmunology