This study shows that nonsense mutations can increase mRNA levels in S. pombe, challenging the conventional understanding of NMD and its impact on transcript abundance.

Biology Open · Mar 30, 2026Peer-reviewedMolecular Biology

Genome-wide chromosomal association of Upf1 is linked to Pol II transcription in Schizosaccharomyces pombe

Sandip De, David M. Edwards, Vibha Dwivedi, Jianming Wang, Wazeer Varsally, Hannah L Dixon, Anand Kumar Singh, Precious O. Owuamalam, Matthew T Wright, R. Summers, Md Nazmul Hossain, Emily M Price, Marcin Wlodzimierz Wojewodzic, Francesco Falciani B, Nikolas John Hodges, , Saverio Brogna

This paper reports genome-wide ChIP data showing Upf1 associates with active genes in S. pombe, correlating with Pol II transcription and mRNA levels, and reveals transcriptional defects in Upf1-deficient cells.

Nucleic Acids Research · Dec 6, 2021Peer-reviewedMolecular Biology

Conglomeration of highly antigenic nucleoproteins to inaugurate a heterosubtypic next generation vaccine candidate against Arenaviridae family

Kazi Faizul Azim, Tahera Lasker, Rahima Akter, Mantasha Mahmud Hia, Omar Faruk Bhuiyan, Mahmudul Hasan, Md Nazmul Hossain

The paper designs a heterosubtypic vaccine candidate against Arenaviridae by identifying conserved epitopes from nucleoproteins of multiple viruses and evaluating their immunogenicity and compatibility for expression.

bioRxiv · Dec 29, 2019 · PreprintBioinformatics

Contriving a chimeric polyvalent vaccine to prevent infections caused by Herpes Simplex Virus (Type-1 and Type-2): an exploratory immunoinformatic approach

Mahmudul Hasan, Shiful Islam, Sourav Chakraborty, Abu Hasnat Mustafa, Kazi Faizul Azim, Ziaul Faruque Joy, Md Nazmul Hossain, Shakhawat Hossain Foysal, Md. Nazmul Hasan

The paper designs a chimeric polyvalent vaccine against HSV-1 and HSV-2 using immunoinformatic methods to identify and combine epitopes from six viral proteins.

Journal of Biomolecular Structure and Dynamics · Jul 22, 2019Peer-reviewedBioinformatics