Author

Jianming Wang

University of BirminghamORCID 0000-0002-9151-284XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anand Kumar SinghiD· 2 shared Daniel HebenstreitiD· 2 shared Marco SaponaroiD· 2 shared Saverio BrognaiD· 2 shared Vibha DwivediiD· 2 shared Claus M. AzzaliniD· 1 shared David M. EdwardsiD· 1 shared Emily M Price· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anand Kumar SinghORCID

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3 papers

Recent·Most cited

Genome-wide chromosomal association of Upf1 is linked to Pol II transcription in Schizosaccharomyces pombe

Sandip De, David M. Edwards, Vibha Dwivedi, Jianming Wang, Wazeer Varsally, Hannah L Dixon, Anand Kumar Singh, Precious O. Owuamalam, Matthew T Wright, R. Summers, Md Nazmul Hossain, Emily M Price, Marcin Wlodzimierz Wojewodzic, Francesco Falciani B, Nikolas John Hodges, , Saverio Brogna

This paper reports genome-wide ChIP data showing Upf1 associates with active genes in S. pombe, correlating with Pol II transcription and mRNA levels, and reveals transcriptional defects in Upf1-deficient cells.

Nucleic Acids Research · Dec 6, 2021Peer-reviewedMolecular Biology

RPRD Proteins Control Transcription in Human Cells

Kinga Winczura, Hurmuz Ceylan, Monika Śledziowska, Matt Jones, Holly Fagarasan, Jianming Wang, Marco Saponaro, Roland R. Arnold, Daniel Hebenstreit, Pawel Grzechnik

This study identifies RPRD proteins as negative regulators of transcription in human cells, showing their inverse correlation with RNA accumulation and their role in forming complexes with Pol II.

bioRxiv · Jun 20, 2021 · PreprintMolecular Biology

An intron proximal to a PTC enhances NMD in Saccharomyces cerevisiae

Jikai Wen, Muyang He, Marija Petrić, Laetitia Marzi, Jianming Wang, Kim Piechocki, Tina McLeod, Anand Kumar Singh, Vibha Dwivedi, Saverio Brogna

The paper shows that an intron near a PTC enhances NMD in S. cerevisiae, independent of EJC and splicing direction.

bioRxiv · Mar 18, 2020 · PreprintMolecular Biology