Justin A. Boddey

This paper demonstrates that chemovaccination using antimalarials targeting plasmepsin IX/X induces durable immunity against malaria in mice and shows conservation of the mechanism in P. falciparum.

The paper develops a CRISPR-based system using Cas9-expressing hepatocytes to study Plasmodium falciparum host interactions, validating its utility for screening host genes involved in infection.

The paper identifies temporal expression patterns of liver-stage malaria antigens and shows that combining antigens with different temporal profiles improves vaccine efficacy.

The paper shows iron deficiency reduces Plasmodium parasitemia in pregnant women and mice, and iron supplementation does not increase parasitemia when combined with malaria prevention.

The paper identifies LSA3 as an exported protein essential for Plasmodium falciparum liver-stage development and presents it as a potential vaccine candidate.

The paper shows that azithromycin resistance in malaria parasites reduces their transmission via mosquitoes, suggesting it could help control drug resistance.

This study identifies ASP5 substrates in Toxoplasma gondii, revealing their role in maturing virulence factors within the parasitophorous vacuole.