Satoshi Yoshinaga

This study shows that disrupting developmental myelination in the medial prefrontal cortex impairs adult social behavior and PV interneuron function in mice, with parallels in human schizophrenia.

The paper profiles NHD microglia and shows they adopt an antigen-presenting state without TREM2 dependence, triggering glial-to-neuronal changes.

The paper identifies altered layer 1 astrocytes in schizophrenia using spatial and single-nucleus transcriptomics of the anterior cingulate cortex.

The paper constructs a single-cell atlas of transcribed cis-regulatory elements in the human genome, revealing gene regulation patterns and trait-gene relationships across cell populations.

The paper uses FlashTag labeling to show regional differences in neuronal migration in the developing mouse cortex, which thymidine analogues cannot capture.

This study uses two-photon voltage imaging to record electrical activity from multiple neurons in brain slices, revealing network connectivity with single-trial resolution.