Author

Loı̈c Dupré

Centre National de la Recherche ScientifiqueORCID 0000-0002-7278-6503Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandra Rodak· 1 shared Angelika Plach· 1 shared Anton KamneviD· 1 shared Christoph MadritschiD· 1 shared Christopher W. FelliD· 1 shared Dirk Hans BuschiD· 1 shared Hannes S. J. StockingeriD· 1 shared Iago Doel PereziD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Aleksandra Rodak

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Deconstructing CTL-mediated autoimmunity through weak TCR-cross-reactivity towards highly abundant self-antigen

Angelika Plach, Vanessa Mühlgrabner, Aleksandra Rodak, René Platzer, Iago Doel Perez, Paul Fellinger, Timo Peters, Yvonne Winhofer, Christoph Madritsch, Lukas Schrangl, Hannes S. J. Stockinger, Loı̈c Dupré, Dirk Hans Busch, Kilian Schober, Janett Göhring, Johannes B. Huppa

The paper uses live-cell imaging to study TCR:pMHC interactions in anti-viral and autoimmunity settings, revealing differences in synaptic engagement, CD8 co-engagement, and signaling efficiency that define central tolerance boundaries.

bioRxiv · Aug 17, 2024 · PreprintImmunology

BioProfiling.jl: Profiling biological perturbations with high-content imaging in single cells and heterogeneous populations

Loan Vulliard, Joel Hancock, Anton Kamnev, Christopher W. Fell, Joana Ferreira da Silva, Joanna I. Loizou, Vanja Nagy, Loı̈c Dupré, Jörg Menche

BioProfiling.jl provides a Julia package for morphological profiling of high-content imaging data, enabling analysis of cell state changes and integration with molecular target networks.

Bioinformatics · Dec 16, 2021Peer-reviewedBioinformatics