Cell BiologybioRxivPreprint
Inhibitor-2 directs formation of PP1 holoenzymes through a docking motif-dependent transfer of catalytic subunits to adapters
Neha Varshney, Aleesa J. Schlientz, Johnathan L. Meaders…·Arshad B. Desai
The paper shows Inhibitor-2 facilitates PP1 holoenzyme formation by transferring catalytic subunits to adapters via its RVxF docking motif, with mutations disrupting this process.
DOI 10.64898/2026.03.15.711929