Patricia A. Thibault

Epigenetic Control of TERRA by FTSJ3 is Critical for Telomerase-Driven Cancers

The paper identifies FTSJ3 as a critical vulnerability in hTERT-overexpressing cancers by showing its role in TERRA methylation and telomeric heterochromatin stability.

A temperature-sensitive and interferon-silent Sendai virus vector for CRISPR-Cas9 delivery and gene editing in primary human cells

This paper develops a temperature-sensitive and interferon-silent Sendai virus vector for CRISPR-Cas9 delivery, achieving high gene editing efficiency in human cells without triggering immune responses.

Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm

This study identifies how paramyxovirus matrix proteins inhibit host cell translation by interacting with the exon-junction complex, enhancing viral replication.