Author

Christian S. Stevens

Icahn School of Medicine at Mount SinaiORCID 0000-0003-2472-6984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Benhur LeeiD· 5 shared Shreyas KowdleiD· 4 shared Alexander N. FreibergiD· 2 shared Arnold ParkiD· 2 shared Chuan-Tien HungiD· 2 shared Griffin D. HaasiD· 2 shared Hsin-Ping ChiuiD· 2 shared Patricia A. ThibaultiD· 2 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

Benhur LeeORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedNov 4, 2024

A temperature-sensitive and interferon-silent Sendai virus vector for CRISPR-Cas9 delivery and gene editing in primary human cells

Christian S. Stevens, Jillian C. Carmichael, Ruth Watkinson…·Benhur Lee

This paper develops a temperature-sensitive and interferon-silent Sendai virus vector for CRISPR-Cas9 delivery, achieving high gene editing efficiency in human cells without triggering immune responses.

5 citations

humanCRISPR screen

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MicrobiologybioRxivPreprintSep 5, 2024

Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm

Chuan-Tien Hung, Griffin D. Haas, Ruth E Watkinson…·Benhur Lee

This study identifies how paramyxovirus matrix proteins inhibit host cell translation by interacting with the exon-junction complex, enhancing viral replication.

DOI 10.1101/2024.09.05.611502

proteomicsexperimental assay

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ImmunologybioRxivPreprintMar 26, 2024

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies

John Beaulaurier, Lynn Ly, J. Andrew Duty…·Benhur Lee

This study uses single-cell transcriptomics and germline haplotype assembly to discover antibodies from human blood post-MMR vaccination, showing neutralization of measles virus.

3 citations

humanscRNA-seq

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Molecular BiologyJournal of VirologyPeer-reviewedMar 1, 2024

Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes

Kasopefoluwa Y. Oguntuyo, Griffin D. Haas, Kristopher D. Azarm…·Benhur Lee

7 citations

experimental assay

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Molecular BiologyEmerging Microbes & InfectionsPeer-reviewedDec 29, 2020

SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts.

Mehdi Denis Moustaqil, Emma Ollivier, Hsin-Ping Chiu…·Yann Gambin

This study identifies SARS-CoV-2 proteases NSP3 and NSP5 cleaving IRF3, NLRP12, and TAB1, which modulate inflammatory pathways, and explores implications for disease across species and potential reservoir hosts.

286 citationstop 3%

humanmouse

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