Author

Anton Jan Venhuizen

University Medical Center UtrechtORCID 0000-0002-7314-1467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Despina Xanthakis· 1 shared Ingrid JordensiD· 1 shared Madelon M. MauriceiD· 1 shared Marleen T. AartsiD· 1 shared Milo L. KapteiniD· 1 shared Yvanka van Os· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Despina Xanthakis

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1 paper

Recent·Most cited

Cancer BiologyiSciencePeer-reviewedDec 20, 2025

Hepatocellular carcinoma-associated AXIN1 mutations drive low levels of Wnt/β-catenin pathway activity that allow for niche-independent growth and YAP/TAZ signaling

Anton Jan Venhuizen, Yvanka van Os, Milo L. Kaptein…·Madelon M. Maurice

This study shows that AXIN1 mutations in HCC lead to reduced Wnt/β-catenin activity and increased YAP/TAZ signaling, enabling niche-independent growth.

3 citations

humanproteomics

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