Marleen T. Aarts

This study shows that AXIN1 mutations in HCC lead to reduced Wnt/β-catenin activity and increased YAP/TAZ signaling, enabling niche-independent growth.

This study identifies GRHL2 as a co-regulator of PR in breast cancer cells, showing their interaction and shared regulation of gene enhancers through chromatin looping.

The paper identifies GRHL and PGR proteins as regulators of WNT4 expression in mammary glands through 3D chromatin looping mechanisms.