WNT7B drives a program for pancreatic cancer subtype switching and progression
Joep Sprangers, Jeroen M. Bugter, Despina Xanthakis, Michiel Boekhout, Rutger N.U. Kok, Veerle Geurts, Hans C. Clevers, Lodewijk A.A. Brosens, Frederike Dijk, Maria J. Rodríguez Colman, Jelte van der Vaart, Madelon M. Maurice
This study shows WNT7B drives pancreatic cancer subtype switching and progression by promoting a basal-like state and influencing cell communication within tumors.
iScience · Feb 17, 2026Peer-reviewedCancer Biology