Mario Ostrowski

This paper studies HIV superinfection to show how immune responses shape rebound dynamics and reservoir reactivation during treatment interruption.

This study investigates immune responses to SARS-CoV-2 and EBV in neuropsychiatric long COVID patients and finds reduced EBV neutralization linked to persistent fatigue.

This study shows antigen stimulation drives clonal expansion of latent HIV-infected CD4+ T cells through TCR and co-stimulatory signals, with IL-7 and CD28 playing key roles.

This study develops a tool to analyze transposable element expression in single-cell RNA sequencing data and builds an atlas showing TEs delineate cell types in human PBMCs.

This study uses machine learning to identify immunogenic signatures of Th1 imprinting in HIV-positive individuals on ART after repeated SARS-CoV-2 vaccination, highlighting saliva-based antibody screening as a potential diagnostic feature.

This study examines how mRNA vaccine-induced T-cell responses correlate with neutralizing antibodies and how pre-existing immunity affects vaccine responses over time.

The paper evaluates the Intact Proviral DNA Assay (IPDA) for HIV reservoir quantification, finding that HIV diversity leads to a 28% failure rate and underestimation of reservoir size.

Telescope accurately estimates transposable element expression in RNA-seq data by resolving ambiguously mapped fragments using a Bayesian model, revealing cell-type specific retrotranscriptome differences.