Author

Patrick Budylowski

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Furkan GuvenciD· 2 shared Mario OstrowskiiD· 2 shared Natasha Christie-HolmesiD· 2 shared Philip Samaan· 2 shared Samira MubarekaiD· 2 shared Scott D. Gray‐OweniD· 2 shared Adrian Granda FariasiD· 1 shared Adrian Pasculescu· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersSystems Biology

Furkan GuvencORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Diminished EBV-Specific Humoral Immunity is Associated with Neuropsychiatric Long COVID Development up to 12 Months Post-COVID-19 Symptom Onset

Philip Samaan, Patrick Budylowski, Victoria Rose Russell, Jeevitha Srighanthan, Angela M. Cheung, Mario Ostrowski

This study investigates immune responses to SARS-CoV-2 and EBV in neuropsychiatric long COVID patients and finds reduced EBV neutralization linked to persistent fatigue.

bioRxiv · Jan 28, 2026 · PreprintImmunology

mRNA Vaccine-Induced SARS-CoV-2 Spike-Specific IFN-γ and IL-2 T-cell Responses are Predictive of Serological Neutralization and are Transiently Enhanced by Pre-Existing Cross-Reactive Immunity

Philip Samaan, Chapin S. Korosec, Patrick Budylowski, S. L. L. Chau, Adrian Pasculescu, Freda Qi, Melanie Delgado-Brand, Tulunay R. Tursun, Geneviève Mailhot, Roya Monica Dayam, Corey R. Arnold, Marc‐André Langlois, Justin Mendoza, Thomas Morningstar, Ryan Law, , Mario Ostrowski

This study examines how mRNA vaccine-induced T-cell responses correlate with neutralizing antibodies and how pre-existing immunity affects vaccine responses over time.

Journal of Virology · Jan 31, 2025Peer-reviewedImmunology

Systematic genome-scale identification of host factors for SARS-CoV-2 infection across models yields a core single gene dependency; ACE2

Katherine Chan, Adrian Granda Farias, Hunsang Lee, Furkan Guvenc, Patricia Mero, Kamaldeep Aulakh, Kevin R. Brown, Shahan Haider, Edyta Marcon, Ulrich Braunschweig, Amy H.Y. Tong, Shuye Pu, Andrea Habsid, Natasha Christie-Holmes, Patrick Budylowski, , Jason Moffat

The paper identifies ACE2 as the only common host dependency for SARS-CoV-2 across multiple cell lines, while other host factors are cell line specific.

bioRxiv · Jun 28, 2021 · PreprintSystems Biology

Multivalency transforms SARS-CoV-2 antibodies into broad and ultrapotent neutralizers

Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A. Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C. Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, , Jean‐Philippe Julien

The paper describes a multimerization platform that transforms antibodies into potent, broad-spectrum neutralizers against SARS-CoV-2.

Nature Communications · Jun 16, 2021Peer-reviewedMolecular Biology