Author

Geoffrey A. Bocobo

Brigham and Women's HospitalORCID 0000-0002-7392-5376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Paul B. YuiD· 2 shared Agustin H. Mohedas· 1 shared Alex N. BullockiD· 1 shared Ana Zeghibe· 1 shared Aris N. EconomidesiD· 1 shared Arthur M. LeeiD· 1 shared Christine Huard· 1 shared Devaveena DeyiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

Paul B. YuORCID

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2 papers

Recent·Most cited

BMP9 regulates the endothelial secretome to drive pulmonary hypertension

Ying Zhong, Peiran B Yang, Luca Troncone, Oleg V. Kovalenko, Eva Maria Fast, Shreyas Rajesh, Sydney Lavoie, Kathleen E. Tumelty, Elizabeth Shin, Taylor A. Covington, Ana Zeghibe, Marc H. Wadsworth, Stephen M. Christensen, Robin S. Nathans, Susan Benard, , Paul B. Yu

This study shows that inhibiting BMP9 signaling reduces endothelial secretion of vasoactive factors that drive pulmonary vascular remodeling in pulmonary hypertension.

bioRxiv · Aug 29, 2025 · PreprintPhysiology

Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva

Eleanor Williams, Jana Bagarova, Georgina Kerr, Dong-Dong Xia, Elsie Place, Devaveena Dey, Yue Shen, Geoffrey A. Bocobo, Agustin H. Mohedas, Xiuli Huang, Philip E.J. Sanderson, Arthur M. Lee, Wei Zheng, Aris N. Economides, James C. Smith, , Alex N. Bullock

The paper identifies saracatinib as a potent ALK2 inhibitor effective in preventing heterotopic ossification in FOP models.

JCI Insight · Mar 11, 2021Peer-reviewedMolecular Biology