Author

Alexander von der Malsburg

Goethe University FrankfurtORCID 0000-0002-7412-2276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aamna JainiD· 1 shared Aleksandra TrifunovićiD· 1 shared Christine ZargesiD· 1 shared Claudia GötziD· 1 shared Cynthia AlsayyahiD· 1 shared Jan RiemeriD· 1 shared John F. ReinhardiD· 1 shared Joseph Helmuth LorentiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Aamna JainORCID

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2 papers

Recent·Most cited

Mammalian MemPrep establishes the lipid composition of ER membranes in HEK293T cells

Aamna Jain, Alexander von der Malsburg, Cynthia Alsayyah, Claudia Götz, Mohamed Elmofty, John F. Reinhard, Per Haberkant, Volkhard Helms, Joseph Helmuth Lorent, Robert Ernst

This study characterizes the lipid composition of mammalian ER membranes using MemPrep, showing a common lipid profile across ER subdomains and linking lipid and protein biophysical properties.

bioRxiv · Jun 19, 2026 · PreprintCell Biology

Topology control by a conserved cysteine pair in the OMM-protein CCDC127 enables MICOS interaction

Christine Zarges, Pauline Schepsky, Robin Alexander Rothemann, Tobias Bock-Bierbaum, Alexander von der Malsburg, Linda C. Baumann, Aleksandra Trifunović, Oliver Daumke, Martin van der Laan, Karina von der Malsburg, Jan Riemer

The paper identifies CCDC127 as a mitochondrial disulfide relay substrate that interacts with MICOS components, revealing its role in OMM topology and mitochondrial membrane organization.

bioRxiv · Dec 15, 2025 · PreprintBiochemistry