Scott A. Wilke

This study identifies a cell type-specific mechanism in the prefrontal cortex that underlies the rapid antidepressant effects of a specific rTMS protocol in a mouse model.

This study shows that dopamine signaling in the VTA-mPFC circuit is essential for rapid threat avoidance learning, with transient dopamine activity encoding aversive outcomes and predictive cues.

This study investigates how prefrontal cortex activity changes during rapid threat avoidance learning in mice, finding that population dynamics precede single-neuron encoding changes.

This study shows that microglia are essential for excitatory synapse formation in the nucleus accumbens during early development, impacting threat avoidance behaviors in adulthood.

BehaviorDEPOT automates behavior classification and analysis in rodents, providing tools for tracking, classification, and experimental setup with reduced costs and improved reliability.

This study shows that neural activity in the anterior cingulate cortex is necessary for making effort-based decisions by using optogenetic manipulation in a mouse model.

The paper identifies that dopamine D2 receptors enhance correlated prefrontal microcircuit activity, which is modulated by antidepressants and linked to stress-coping behaviors.