Microglia regulate nucleus accumbens synaptic development and circuit function underlying threat avoidance behaviors
Michael W. Gongwer, Fanny Etienne, Eric N. Moca, Megan S. Chappell, Sara V. Blagburn-Blanco, Jack P. Riley, Alexander S. Enos, Melody Haratian, Alex Qi, Rocío Rojo, Scott A. Wilke, Clare Pridans, Laura A. DeNardo, Lindsay M. De Biase
This study shows that microglia are essential for excitatory synapse formation in the nucleus accumbens during early development, impacting threat avoidance behaviors in adulthood.
bioRxiv · Jan 15, 2025 · PreprintNeuroscience