Lindsay M. De Biase

This study shows that microglial mitochondria change with brain region, aging, and inflammation, affecting gene expression and morphology.

This study shows that microglia are essential for excitatory synapse formation in the nucleus accumbens during early development, impacting threat avoidance behaviors in adulthood.

This study identifies intercellular signaling pathways involved in vascular dementia repair and demonstrates therapeutic potential through drug intervention.

The paper investigates how microglia and the extracellular matrix influence cognitive aging by analyzing ECM composition, microglial interactions, and their relationship with synapses and behavior.

The paper shows that microglia in specific brain regions exhibit premature aging-related inflammation in middle age, which may affect nearby neurons.

The paper examines microglial development in the basal ganglia of mice, finding region-specific changes in density and lysosome abundance during postnatal development.

The paper quantifies the spatial relationship between NG2+ cells and nodes of Ranvier in the CNS, finding sparse and non-essential interactions.