Author

Patricia Marques

Karolinska InstitutetORCID 0000-0002-7449-837XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Federico PietrocolaiD· 2 shared Alejandro Failde-FiestrasiD· 1 shared Alex Miralles-DomingueziD· 1 shared Aurora Gómez-DurániD· 1 shared Cheng CheniD· 1 shared Christian G. RiedeliD· 1 shared Clara AlconiD· 1 shared Dafni ChondronasiouiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Federico PietrocolaORCID

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2 papers

Recent·Most cited

Pasta, a versatile transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation

Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez-Diaz, Hazel Xiaohui Ang, Federico Pietrocola, Christian G. Riedel

Pasta is a transcriptomic aging clock that predicts biological age across tissues and data types, identifies age-modulatory compounds, and links aging to mitochondrial translation and mRNA splicing.

Advanced Science · Jul 27, 2026Peer-reviewedBioinformatics

SENOMORPHIC EFFECT OF GENETIC AND CHEMICAL PARTIAL REPROGRAMMING

Victor Nuñez-Quintela, Jérémy Chantrel, Miguel Angel Prados, Pablo Pedrosa, Italo Lorandi, Lucia Lorenzo Rodriguez, Cheng Chen, Raquel Paredes-Paredes, Alejandro Failde-Fiestras, Diego Gonzalez‐Perez, Alex Miralles-Dominguez, Sabela Da Silva‐Álvarez, Ramón Lobato-Busto, Miguel González‐Barcia, Clara Alcon, , Manuel Collado

This study shows genetic and chemical partial reprogramming targets senescent cells to reduce aging-related inflammation and improve mitochondrial function in aged mice without restoring proliferation.

bioRxiv · Jan 13, 2026 · PreprintCell Biology