Author
Okinawa Institute of Science and Technology Graduate UniversityORCID 0000-0002-7469-7424Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Ben E. Clifton, Bakhytzhan Akdavletov, Prashant Ankur Jain, Paola Laurino
The paper shows that a spontaneous post-translational succinimide modification in a bacterial solute-binding protein enhances its thermostability and binding affinity for 5-oxoproline.
Prashant Jain, Dariia Yehorova, Ririn Rahmala Febri…·Paola Laurino
The paper identifies a triple-deletion mutant of SRC kinase that alters activation loop dynamics, leading to changes in substrate preference and signaling outcomes.
Ben E. Clifton, Joe A. Kaczmarski, Paul D. Carr…·Colin J. Jackson
This study shows how an enzyme evolved from a solute-binding protein through structural and catalytic changes, highlighting mechanisms of de novo enzyme emergence.