Author

Lisa Spänig

German Cancer Research CenterORCID 0000-0002-7482-0111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Laura Sieber· 2 shared Lena M. KutscheriD· 2 shared Marc ZuckermanniD· 2 shared Mari SeppiD· 2 shared Patricia Benites Goncalves da SilvaiD· 2 shared Adriana Sánchez‐DanésiD· 1 shared Angelina Sanderson· 1 shared Annarita PatriziiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Laura Sieber

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Conserved cerebellar rhombic lip compartmentalization and Eomes regulatory networks govern unipolar brush cell development

Vuslat Akcay, Lisa Spänig, Wouter-Michiel A.M. Vierdag, Piyush Joshi, Patricia Benites Goncalves da Silva, Angelina Sanderson, Robert Reinhardt, Laura Sieber, Nina Hofmann, Jana Nolle, Franziska Schelb, Marc Zuckermann, Henrik Kaessmann, Stefan Michael Pfister, Adriana Sánchez‐Danés, , Lena M. Kutscher

This study shows that Eomes regulates UBC differentiation and migration in mice, mirroring human UBC development, and highlights conserved molecular mechanisms in cerebellar development.

bioRxiv · Jul 28, 2026 · PreprintDevelopmental Biology

Loss of the Familial Dysautonomia gene Elp1 in cerebellar granule cell progenitors leads to ataxia in mice

Frederik Arnskötter, Patricia Benites Goncalves da Silva, Mackenna E. Schouw, Chiara Lukasch, Luca Bianchini, Laura Sieber, Jesús García-López, Shiekh Tanveer Ahmad, Yiran Li, Hong Lin, Piyush K. Joshi, Lisa Spänig, Magdalena Radoš, Mykola Roiuk, Mari Sepp, , Lena M. Kutscher

This study shows that loss of Elp1 in cerebellar granule cell progenitors causes ataxia and cerebellar defects in mice, suggesting a role for ELP1 in FD pathogenesis.

Neurobiology of Disease · Jul 10, 2024Peer-reviewedNeuroscience